Overdoses Involving Medetomidine Mixed with Opioids — Chicago, Illinois, May 2024

Amy Nham, PharmD1,2,*; John N. Le, PharmD1,3,*; Shawn A. Thomas, PhD1,4; Kimberly Gressick, MD1,2; Emily N. Ussery, PhD5; Jean Y. Ko, PhD5; R. Matt Gladden, PhD5; Christina A. Mikosz, MD5; Joshua G. Schier, MD5; Alana Vivolo-Kantor, PhD5; Maria Fiorillo, MPH2; McKenna McMaster, MPH2; Darlene Nolasco Magana, MBA, MPH2; Livia Verklan-McInnes2; Michael Wahl, MD6; Taylor Wood7; […]

Antiretroviral Postexposure Prophylaxis After Sexual, Injection Drug Use, or Other Nonoccupational Exposure to HIV — CDC Recommendations, United States, 2025

Recommendations The following section provides recommendations to clinicians from the beginning of the nPEP evaluation to the completion of nPEP therapy (Box 2). “HIV nPEP Indications” details the situations in which nPEP should and should not be administered. “Time to Initiation of HIV nPEP” stresses rapid initiation of nPEP and explains the rationale behind this […]

Trends in Suspected Fentanyl-Involved Nonfatal Overdose Emergency Department Visits, by Age Group, Sex, and Race and Ethnicity — United States, October 2020–March 2024

Discussion From Q4 2020 through mid-2023, rates of fentanyl-involved nonfatal overdose ED visits increased. Rates subsequently declined through Q1 2024; the declines were observed overall and across a majority of demographic groups. These findings are consistent with recent mortality data, which indicate that overdose deaths with illegally manufactured fentanyl and fentanyl analogs detected peaked in […]

Interim Evaluation of Respiratory Syncytial Virus Hospitalization Rates Among Infants and Young Children After Introduction of Respiratory Syncytial Virus Prevention Products — United States, October 2024–February 2025

Monica E. Patton, MD1,2,*; Heidi L. Moline, MD1,2,*; Michael Whitaker, MPH1; Ayzsa Tannis, MPH1,3; Huong Pham, MPH1; Ariana P. Toepfer, MPH1; Christopher A. Taylor, PhD1; Leah Goldstein, MPH1,4; Arthur Reingold, MD5; Pam Daily Kirley, MPH6; Nisha B. Alden, MPH7; Breanna Kawasaki, MPH7; James Meek, MPH8; Daewi Kim, MPH8; Lucy S. Witt, MD9,10; Kyle P. Openo, […]

Health Care Use Preceding Suicide by Firearm Compared with Suicide by Other Means — Alaska, Colorado, and Washington, 2020–2022

Methods Data Source and Study Population State death records and electronic health records (EHRs) were obtained from three participating nonprofit health care systems, jointly serving more than one million persons. These included the Colorado and Washington regions of Kaiser Permanente, which are integrated insurance and health care providers each serving approximately 500,000 members, and the […]

Notes from the Field: Multistate Outbreak of Salmonella enterica I 4:I:- Infections Linked to Charcuterie-Style Meats — United States, 2023–2024

Angelo Lodato, MPH1,2; Andrea Cote, DVM3; Joshua Rounds, MPH4; Laurie K. Stewart, MS5; Anna E. Pickett5; Megan E. Cahill, PhD6,7; Lorrie L. B. Martin, MS6; Jennifer K. Adams2,8; Lauren Gollarza, MHS2; Zachary D. McCormic, MPH2 (View author affiliations) View suggested citation Summary What is already known about this topic? Three multistate U.S. outbreaks of salmonellosis […]

Cave-Associated Histoplasmosis Outbreak Among Travelers Returning from Costa Rica — Georgia, Texas, and Washington, December 2024–January 2025

Investigation and Outcomes On January 21, CDC launched a multistate investigation in collaboration with the Georgia Department of Public Health, Texas Department of State Health Services, and Washington State Department of Health to identify and characterize cases. This activity was reviewed by CDC, deemed not research, and was conducted consistent with applicable federal law and […]

Enteric Disease Outbreaks Associated with Animal Contact — Animal Contact Outbreak Surveillance System, United States, 2009–2021

Results During 2009–2021, ACOSS received reports of 557 outbreaks, resulting in 14,377 illnesses, 2,656 hospitalizations, and 22 deaths (Figure) (Supplementary Table, https://stacks.cdc.gov/view/cdc/177769#tabs-3). The median number of outbreaks reported per year was 45 (range = 21–62 outbreaks). Single-state outbreaks were reported by 44 states and accounted for 393 (71%) outbreaks and 2,935 (20%) illnesses (median = […]